EBT Secures $10M Series A

11/19/19

EBT Medical, Inc., a clinical-stage startup developing disruptive neuromodulation therapies for pelvic health disorders, recently secured a USD$10M Series A investment, co-led by two top-tier venture capital firms, SV Health Investors and Genesys Capital.

EBT intends to use the funding to further develop its revolutionary noninvasive neuromodulation technology, as well as to pursue additional clinical data validating its safety and effectiveness. Funding will also be used to expand the management team and for general administrative purposes.

"Having SV and Genesys on board is an extremely important step as EBT enters a new phase of growth," said Keith R. Carlton, CEO of EBT. "With their substantial expertise and investment, we will significantly accelerate our efforts to perfect our noninvasive technology, starting with overactive bladder."

EBT is pursuing a new noninvasive approach to treating overactive bladder (OAB), which affects nearly 550M patients worldwide.1 EBT's differentiated approach centers on a new stimulation target—the Saphenous nerve—which can be stimulated noninvasively. Preliminary data suggests similar efficacy to drugs and invasive therapies, but with significantly reduced risk and side effects.

"We are excited to be co-leading EBT's Series A investment alongside Genesys Capital," said Greg Madden, Partner at SV Health. "We believe EBT's patented Saphenous nerve approach is a potential game-changer, enabling the first at-home, noninvasive neuromodulation therapy for OAB. OAB is a massive market with large unmet needs: drugs have dangerous side effects, Botox® requires invasive bladder injections, and existing neuromodulation therapies are also highly invasive, involving spinal implants and needles."

Prior to this Series A, EBT has received substantial support and funding from the following: AGE-WELL (https://agewell-nce.ca), the Canadian Institutes of Health Research (http://www.cihr-irsc.gc.ca), the Global Center for Health Innovation (https://mcic.bioenterprise.com), the Natural Sciences and Engineering Research Council of Canada (https://www.nserc-crsng.gc.ca), Toronto Innovation Acceleration Partners (https://tiap.ca), the Innovations & Partnerships Office at the University of Toronto (http://www.research.utoronto.ca/industry-and-partners/commercialization-at-u-of-t), the University of Toronto Early Stage Technology (UTEST) Program (http://utest.to), and the Connaught Fund at the University of Toronto (http://connaught.research.utoronto.ca). EBT also won the Diamond Prize in the MassChallenge startup competition in late 2018 (https://masschallenge.org).

About EBT Medical

EBT Medical was founded in 2014 with a mission to develop novel neuromodulation technologies that restore control, dignity and independence to those silently suffering from pelvic floor disorders. EBT's first proposed product is a clinical-grade, noninvasive neurostimulator and associated ecosystem for treating overactive bladder (OAB). EBT was founded based on scientific discoveries made at the University of Toronto, and successfully incubated by their startup program, which has helped create over 500 companies in the last 10 years. EBT has a significant patent portfolio encompassing multiple neuromodulation technologies including issued patents on the Saphenous nerve for all pelvic health indications. EBT management team and world-class advisory board have decades of relevant experience in pelvic health, neuromodulation, and consumer health. www.ebtmedical.com

About Genesys Capital

Based in Toronto, Genesys Capital is focused on helping North American entrepreneurs build companies in the high-growth sectors of healthcare and biotechnology. Through its expertise and network, Genesys accelerates the development of commercially viable emerging companies that represent promising life science investment opportunities. Genesys has invested in over 35 early stage biotechnology and medical technology companies including: Affinium Pharmaceuticals (acquired by Debiopharm), Aptinyx, Epocal (Acquired by Alere), Invitae, Ionalytics (acquired by Thermo-Fisher), Naurex (acquired by Allergan), Profound Medical. www.genesyscapital.com

About SV Health Investors

SV Health Investors is a global leader in healthcare and life sciences investing with offices in Boston and London. The SV team has been investing in the United States and Europe for more than 25 years and is currently managing $2.2 billion of assets exclusively on healthcare including: healthcare services and IT, biotechnology and medical device. Notable prior medical device investments include: Aquesys (acquired by Allergan), Entellus Medical (acquired by Stryker), LenSx Lasers (acquired by Alcon) and Sadra Medical (acquired by Boston Scientific). www.svhealthinvestors.com

About Overactive Bladder and Neuromodulation

Overactive bladder is a disabling syndrome affecting nearly 550M people worldwide2. It is characterized by frequent, sudden, uncontrollable urges to void, often followed by incontinence episodes that are embarrassing and significantly impede activities of daily living. The major symptom of OAB, Urge Urinary Incontinence (UUI), is thought to be caused by over-signaling to & from the bladder and the pontine micturition center located in the brain stem. Over 50%3 of those with OAB remain undiagnosed and silently suffer, with marked increases in depression, anxiety, sleeplessness due to nocturia (waking to void), and social isolation. The economic impact of OAB in the United States was estimated at $76B including direct costs and indirect costs such as increased urinary tract infections, falls from running to the bathroom, and absenteeism4. Neuromodulation has been an established therapy for UUI since it was first approved in 1997.

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