Curis Reports Inducement Grants Under NASDAQ Listing Rule 5635(c)(4)

10/8/18

Curis, Inc. (NASDAQ: CRIS), a biotechnology company focused on the development and commercialization of innovative therapeutics for the treatment of cancer, today announced that on October 1, 2018, the independent Compensation Committee of the Board of Directors of Curis approved the grant of inducement stock options to purchase 30,000 shares of Curis common stock to a new employee, with a grant date of October 1, 2018 (the "Q4 2018 Inducement Grant").

The Q4 2018 Inducement Grant has an exercise price per share equal to the closing price of the Company's common stock on October 1, 2018. The stock option has a 10 year term and vests over four years, with 25% of the original number of shares underlying the award vesting on the first anniversary of the employee's date of hire and an additional 6.25% of the original number of shares underlying the award vesting on each successive three-month period thereafter, subject to the employee's continued service with the Company through the respective vesting dates. The stock option was granted as an inducement equity award outside of the Company's Third Amended and Restated 2010 Stock Incentive Plan and was made as an inducement material to the employee's acceptance of employment with the Company.

About Curis, Inc.

Curis is a biotechnology company focused on the development and commercialization of innovative therapeutics for the treatment of cancer, including fimepinostat, which is being investigated in clinical studies in patients with diffuse large B-cell lymphoma (DLBCL) and solid tumors. Curis is also engaged in a collaboration with Aurigene Discovery Technologies Limited, or Aurigene, in the areas of immuno-oncology and precision oncology. As part of this collaboration, Curis has exclusive licenses to oral small molecule antagonists of immune checkpoints, including the programmed death ligand-1 (PDL1)/ V-domain Ig suppressor of T cell activation (VISTA) antagonist, CA-170, and the PDL1/T-cell immunoglobulin and mucin domain containing protein-3 (TIM3) antagonist, CA-327, as well as the Interleukin-1 receptor-associated kinase 4 (IRAK4) kinase inhibitor, CA-4948. CA-170 is currently undergoing testing in a Phase 1 trial in patients with advanced solid tumors and lymphomas, and in a Phase 2 trial in India conducted by Aurigene. CA-4948 is currently undergoing testing in a Phase 1 trial in patients with advanced non-Hodgkin lymphomas. Curis is also party to a collaboration with F. Hoffmann-La Roche Ltd, or Roche, and Genentech Inc., or Genentech, a member of the Roche Group, under which Genentech and Roche are commercializing Erivedge® for the treatment of advanced basal cell carcinoma (BCC). For more information, visit Curis's website at www.curis.com.

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